This file provides a description of downloadable files in TM-MC 2.0. 1. Medicinal material This is a list of medicinal materials provided by TM-MC 2.0 that were listed in the Korean, Chinese, and Japanese pharmacopoeias. Medicinal materials were distinguished by their scientific names. Due to differences between pharmacopoeias, a single medicinal material in one pharmacopoeia may map to two medicinal materials in another pharmacopoeia. - Latin: the latin name of a medicinal material, which is the identifier of medicinal materials in TM-MC. (Mandatory) - Common: the english name of a medicinal material as described in pharmacopoeias. (Optional) - Korean: the Korean name of a medicinal material. (Mandatory) - Hanja: the hanja name of a medicinal material. (Optional) - Chinese: the Chinese name of a medicinal material. (Optional) - Pinyin: the pinyin name of a medicinal material. (Optional) - Japanese: the Japanese name of a medicinal material. (Optional) - Kanji: the kanji name of a medicinal material. (Optional) 2. Medicinal compound This is a list of chemical compounds of medicinal materials, which have been curated from PubMed articles. All compounds have an identified TM-MC ID, and unidentified compounds have an ID of 0. - Latin: the latin name of a medicinal material. (Mandatory) - ID: the identified TM-MC ID. (Mandatory) - Compound: the compound name. (Mandatory) - PMID: the PubMed ID from which a compound has been extracted and curated. (Mandatory) 3. Chemical property This contains identifiers and pharmacokinetic properties for identified compounds. - ID: the identified TM-MC ID of a compound. (Mandatory) - InChIKey: the InChIKey of a compound. (Mandatory) - SMILES: the SMILES string of a compound. (Mandatory) - SDF: structure-data format. (Mandatory) - CID: the PubChem Compound ID of a compound. (Optional) - Formula: the molecular formula of a compound. (Mandatory) - MW: the molecular weight. (Mandatory) - Extract_MW: the exact molecular weight. (Mandatory) - LogP: the octanol-water partition coefficient. (Mandatory) - TPSA: the topological polar surface area. (Mandatory) - ATOM: the number of atoms. (Mandatory) - HBA: the number of hydrogen bond acceptors. (Mandatory) - HBD: the number of hydrogen bond donors. (Mandatory) - ROTB: the number of rotatable bonds. (Mandatory) - AROM: the number of aromatic rings. (Mandatory) - ALERTS: the number of structural alerts. (Mandatory) - DL: the drug likeness. (Mandatory) - OB: the oral bioavailability. (Mandatory) 4. Chemical protein This provides the mapping for compounds in TM-MC 2.0 and proteins in STITCH v5.0. Recently, target information interacting with TM-MC compounds from PubChem was updated. - ID: the identified TM-MC ID of a compound. (Mandatory) - ProteinID: the protein ID in STITCH v5.0 mapped to compound IDs. (Mandatory) - Preferred_name: the protein name in STITCH v5.0. (Mandatory) - Source: STITCH or PubChem. (Mandatory) - Score: the combined score provided by STITCH. If the data is from PubChem, the value is 0. (Mandatory) 5. Protein disease This provides the mapping for proteins in STITCH v5.0 and diseases in DisGeNET v7.0. - ProteinID: the protein ID in STITCH v5.0 mapped to compound IDs in TM-MC 2.0. (Mandatory) - Preferred_name : the protein name in STITCH v5.0. (Mandatory) - DiseaseID: the disease ID in DisGeNET v7.0 mapped to protein IDs. (Mandatory) - DiseaseName: the disease name in DisGeNET v7.0. (Mandatory) - Score: the score provided by DisGeNET. (Mandatory) 6. Prescription - English: the english name of a prescription, which has been converted according to the romanization of Korean name. (Mandatory) - Korean: the Korean name of a prescription. (Mandatory) - Hanja: the hanja name of a prescription. (Mandatory) - Chinese: the Chinese name of a prescription. (Mandatory) - Pinyin: the pinyin name of a prescription. (Mandatory) - Written: the ancient literature referenced by a prescription. (Optional) - Chapter: the chapter in the ancient literature referenced by a prescription. (Optional) - Textbook: the textbook from which a prescription was extracted. (Mandatory) - Page: the page number in the textbook from which a prescription was extracted. (Mandatory) - Latin: the latin name of medicinal materials in a prescription. (Mandatory) - Seq: the order of medicinal materials in a prescription. (Mandatory) - Process: the processing method of medicinal materials in a prescription. (Optional) - Dosage: the dosage of medicinal materials in a prescription. (Optional) - Unit: the unit of a dosage. (Optional)